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The Tumor Microenvironment Factors That Promote Resistance to Immune Checkpoint Blockade Therapy
Through genetic and epigenetic alterations, cancer cells present the immune system with a diversity of antigens or neoantigens, which the organism must distinguish from self. The immune system responds to neoantigens by activating naïve T cells, which mount an anticancer cytotoxic response. T cell a...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276693/ https://www.ncbi.nlm.nih.gov/pubmed/34268109 http://dx.doi.org/10.3389/fonc.2021.641428 |