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The Tumor Microenvironment Factors That Promote Resistance to Immune Checkpoint Blockade Therapy

Through genetic and epigenetic alterations, cancer cells present the immune system with a diversity of antigens or neoantigens, which the organism must distinguish from self. The immune system responds to neoantigens by activating naïve T cells, which mount an anticancer cytotoxic response. T cell a...

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Detalles Bibliográficos
Autores principales:	Russell, Bonnie L., Sooklal, Selisha A., Malindisa, Sibusiso T., Daka, Lembelani Jonathan, Ntwasa, Monde
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276693/ https://www.ncbi.nlm.nih.gov/pubmed/34268109 http://dx.doi.org/10.3389/fonc.2021.641428

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