Selective Inhibition of Phosphodiesterase 7 Enzymes Reduces Motivation for Nicotine Use through Modulation of Mesolimbic Dopaminergic Transmission

Approximately 5 million people die from diseases related to nicotine addiction and tobacco use each year. The nicotine-induced increase of corticomesolimbic dopaminergic (DAergic) transmission and hypodopaminergic conditions occurring during abstinence are important for maintaining drug-use habits....

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Detalles Bibliográficos
Autores principales: Ciccocioppo, Roberto, de Guglielmo, Giordano, Li, Hong Wu, Melis, Miriam, Caffino, Lucia, Shen, Quienwei, Domi, Ana, Fumagalli, Fabio, Demopulos, Gregory A., Gaitanaris, George A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276738/
https://www.ncbi.nlm.nih.gov/pubmed/34083258
http://dx.doi.org/10.1523/JNEUROSCI.3180-20.2021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276738/
https://www.ncbi.nlm.nih.gov/pubmed/34083258
http://dx.doi.org/10.1523/JNEUROSCI.3180-20.2021

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