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Selective Inhibition of Phosphodiesterase 7 Enzymes Reduces Motivation for Nicotine Use through Modulation of Mesolimbic Dopaminergic Transmission

Approximately 5 million people die from diseases related to nicotine addiction and tobacco use each year. The nicotine-induced increase of corticomesolimbic dopaminergic (DAergic) transmission and hypodopaminergic conditions occurring during abstinence are important for maintaining drug-use habits....

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Detalles Bibliográficos
Autores principales:	Ciccocioppo, Roberto, de Guglielmo, Giordano, Li, Hong Wu, Melis, Miriam, Caffino, Lucia, Shen, Quienwei, Domi, Ana, Fumagalli, Fabio, Demopulos, Gregory A., Gaitanaris, George A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for Neuroscience 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276738/ https://www.ncbi.nlm.nih.gov/pubmed/34083258 http://dx.doi.org/10.1523/JNEUROSCI.3180-20.2021

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