Evolutionary insights into the furin cleavage sites of SARS-CoV-2 variants from humans and animals

The SARS-CoV-2 spike protein Q677P/H mutation and furin cleavage site (FCS) have been shown to affect cell tropism and virus transmissibility. Here, we analyzed the frequency of Q677P/H and FCS point mutations in 1,144,793 human and 1042 animal spike protein sequences and from those of the emergent...

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Detalles Bibliográficos
Autores principales: Nagy, Abdou, Basiouni, Shereen, Parvin, Rokshana, Hafez, Hafez M., Shehata, Awad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276844/
https://www.ncbi.nlm.nih.gov/pubmed/34258664
http://dx.doi.org/10.1007/s00705-021-05166-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276844/
https://www.ncbi.nlm.nih.gov/pubmed/34258664
http://dx.doi.org/10.1007/s00705-021-05166-z

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