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Adipose Tissue Inflammation Is Directly Linked to Obesity-Induced Insulin Resistance, while Gut Dysbiosis and Mitochondrial Dysfunction Are Not Required

Obesity is associated with adipose tissue hypertrophy, systemic inflammation, mitochondrial dysfunction, and intestinal dysbiosis. Rodent models of high-fat diet (HFD)-feeding or genetic deletion of multifunctional proteins involved in immunity and metabolism are often used to probe the etiology of...

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Detalles Bibliográficos
Autores principales: Petrick, Heather L, Foley, Kevin P, Zlitni, Soumaya, Brunetta, Henver S, Paglialunga, Sabina, Miotto, Paula M, Politis-Barber, Valerie, O’Dwyer, Conor, Philbrick, Diana J, Fullerton, Morgan D, Schertzer, Jonathan D, Holloway, Graham P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276887/
https://www.ncbi.nlm.nih.gov/pubmed/34278304
http://dx.doi.org/10.1093/function/zqaa013