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Adipose Tissue Inflammation Is Directly Linked to Obesity-Induced Insulin Resistance, while Gut Dysbiosis and Mitochondrial Dysfunction Are Not Required
Obesity is associated with adipose tissue hypertrophy, systemic inflammation, mitochondrial dysfunction, and intestinal dysbiosis. Rodent models of high-fat diet (HFD)-feeding or genetic deletion of multifunctional proteins involved in immunity and metabolism are often used to probe the etiology of...
Autores principales: | Petrick, Heather L, Foley, Kevin P, Zlitni, Soumaya, Brunetta, Henver S, Paglialunga, Sabina, Miotto, Paula M, Politis-Barber, Valerie, O’Dwyer, Conor, Philbrick, Diana J, Fullerton, Morgan D, Schertzer, Jonathan D, Holloway, Graham P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276887/ https://www.ncbi.nlm.nih.gov/pubmed/34278304 http://dx.doi.org/10.1093/function/zqaa013 |
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