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A fluorescent target-guided Paal–Knorr reaction

It has become increasingly apparent that high-diversity chemical reactions play a significant role in the discovery of bioactive small molecules. Here, we describe an expanse of this paradigm, combining a ‘target-guided synthesis’ concept with Paal–Knorr chemistry applied to the preparation of fluor...

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Detalles Bibliográficos
Autores principales: Wagh, Sachin B., Maslivetc, Vladimir, La Clair, James J., Kornienko, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276889/
https://www.ncbi.nlm.nih.gov/pubmed/34262697
http://dx.doi.org/10.1039/d0ra06962k