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Inhibition of RPS6K reveals context-dependent Akt activity in luminal breast cancer cells

Aberrant signaling through insulin (Ins) and insulin-like growth factor I (IGF1) receptors contribute to the risk and advancement of many cancer types by activating cell survival cascades. Similarities between these pathways have thus far prevented the development of pharmacological interventions th...

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Detalles Bibliográficos
Autores principales: Erdem, Cemal, Lee, Adrian V., Taylor, D. Lansing, Lezon, Timothy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277016/
https://www.ncbi.nlm.nih.gov/pubmed/34191793
http://dx.doi.org/10.1371/journal.pcbi.1009125