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Inhibition of RPS6K reveals context-dependent Akt activity in luminal breast cancer cells
Aberrant signaling through insulin (Ins) and insulin-like growth factor I (IGF1) receptors contribute to the risk and advancement of many cancer types by activating cell survival cascades. Similarities between these pathways have thus far prevented the development of pharmacological interventions th...
Autores principales: | Erdem, Cemal, Lee, Adrian V., Taylor, D. Lansing, Lezon, Timothy R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277016/ https://www.ncbi.nlm.nih.gov/pubmed/34191793 http://dx.doi.org/10.1371/journal.pcbi.1009125 |
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