Os(II)-Bridged Polyarginine Conjugates: The Additive Effects of Peptides in Promoting or Preventing Permeation in Cells and Multicellular Tumor Spheroids

[Image: see text] The preparation of two polyarginine conjugates of the complex Os(II) [bis-(4′-(4-carboxyphenyl)-2,2′:6′,2″-terpyridine)] [Os-(R(n))(2)](x+) (n = 4 and 8; x = 10 and 18) is reported, to explore whether the R8 peptide sequence that promotes cell uptake requires a contiguous amino aci...

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Detalles Bibliográficos
Autores principales: Gkika, Karmel S., Noorani, Sara, Walsh, Naomi, Keyes, Tia E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277133/
https://www.ncbi.nlm.nih.gov/pubmed/33978399
http://dx.doi.org/10.1021/acs.inorgchem.1c00769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277133/
https://www.ncbi.nlm.nih.gov/pubmed/33978399
http://dx.doi.org/10.1021/acs.inorgchem.1c00769

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