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Os(II)-Bridged Polyarginine Conjugates: The Additive Effects of Peptides in Promoting or Preventing Permeation in Cells and Multicellular Tumor Spheroids
[Image: see text] The preparation of two polyarginine conjugates of the complex Os(II) [bis-(4′-(4-carboxyphenyl)-2,2′:6′,2″-terpyridine)] [Os-(R(n))(2)](x+) (n = 4 and 8; x = 10 and 18) is reported, to explore whether the R8 peptide sequence that promotes cell uptake requires a contiguous amino aci...
Autores principales: | Gkika, Karmel S., Noorani, Sara, Walsh, Naomi, Keyes, Tia E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277133/ https://www.ncbi.nlm.nih.gov/pubmed/33978399 http://dx.doi.org/10.1021/acs.inorgchem.1c00769 |
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