The Incoherent Fluctuation of Folate Pools and Differential Regulation of Folate Enzymes Prioritize Nucleotide Supply in the Zebrafish Model Displaying Folate Deficiency-Induced Microphthalmia and Visual Defects

OBJECTIVE: Congenital eye diseases are multi-factorial and usually cannot be cured. Therefore, proper preventive strategy and understanding the pathomechanism underlying these diseases become important. Deficiency in folate, a water-soluble vitamin B, has been associated with microphthalmia, a conge...

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Detalles Bibliográficos
Autores principales: Hsiao, Tsun-Hsien, Lee, Gang-Hui, Chang, Yi-Sheng, Chen, Bing-Hung, Fu, Tzu-Fun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277299/
https://www.ncbi.nlm.nih.gov/pubmed/34268314
http://dx.doi.org/10.3389/fcell.2021.702969

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277299/
https://www.ncbi.nlm.nih.gov/pubmed/34268314
http://dx.doi.org/10.3389/fcell.2021.702969

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