Synthesis and Initial Characterization of a Reversible, Selective (18)F-Labeled Radiotracer for Human Butyrylcholinesterase

PURPOSE: A neuropathological hallmark of Alzheimer’s disease (AD) is the presence of amyloid-β (Aβ) plaques in the brain, which are observed in a significant number of cognitively normal, older adults as well. In AD, butyrylcholinesterase (BChE) becomes associated with A(β) aggregates, making it a p...

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Detalles Bibliográficos
Autores principales: Gentzsch, Christian, Chen, Xinyu, Spatz, Philipp, Košak, Urban, Knez, Damijan, Nose, Naoko, Gobec, Stanislav, Higuchi, Takahiro, Decker, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277621/
https://www.ncbi.nlm.nih.gov/pubmed/33660167
http://dx.doi.org/10.1007/s11307-021-01584-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277621/
https://www.ncbi.nlm.nih.gov/pubmed/33660167
http://dx.doi.org/10.1007/s11307-021-01584-2

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