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Variability within rare cell states enables multiple paths towards drug resistance

Molecular differences between individual cells can lead to dramatic differences in cell fate, such as death versus survival of cancer cells upon drug treatment. These originating differences remain largely hidden due to difficulties in determining precisely what variable molecular features lead to w...

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Detalles Bibliográficos
Autores principales: Emert, Benjamin L., Cote, Christopher, Torre, Eduardo A., Dardani, Ian P., Jiang, Connie L., Jain, Naveen, Shaffer, Sydney M., Raj, Arjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277666/
https://www.ncbi.nlm.nih.gov/pubmed/33619394
http://dx.doi.org/10.1038/s41587-021-00837-3