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Variability within rare cell states enables multiple paths towards drug resistance
Molecular differences between individual cells can lead to dramatic differences in cell fate, such as death versus survival of cancer cells upon drug treatment. These originating differences remain largely hidden due to difficulties in determining precisely what variable molecular features lead to w...
Autores principales: | Emert, Benjamin L., Cote, Christopher, Torre, Eduardo A., Dardani, Ian P., Jiang, Connie L., Jain, Naveen, Shaffer, Sydney M., Raj, Arjun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277666/ https://www.ncbi.nlm.nih.gov/pubmed/33619394 http://dx.doi.org/10.1038/s41587-021-00837-3 |
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