CVN‐AD Alzheimer's mice show premature reduction in neurovascular coupling in response to spreading depression and anoxia compared to aged controls

We compared the efficacy of neurovascular coupling and substrate supply in cerebral cortex during severe metabolic challenges in transgenic Alzheimer's [CVN‐AD] and control [C57Bl/6] mice, to evaluate the hypothesis that metabolic insufficiency is a critical component of degeneration leading to...

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Detalles Bibliográficos
Autores principales: Turner, Dennis A., Degan, Simone, Hoffmann, Ulrike, Galeffi, Francesca, Colton, Carol A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277667/
https://www.ncbi.nlm.nih.gov/pubmed/33656270
http://dx.doi.org/10.1002/alz.12289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277667/
https://www.ncbi.nlm.nih.gov/pubmed/33656270
http://dx.doi.org/10.1002/alz.12289

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