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CVN‐AD Alzheimer's mice show premature reduction in neurovascular coupling in response to spreading depression and anoxia compared to aged controls
We compared the efficacy of neurovascular coupling and substrate supply in cerebral cortex during severe metabolic challenges in transgenic Alzheimer's [CVN‐AD] and control [C57Bl/6] mice, to evaluate the hypothesis that metabolic insufficiency is a critical component of degeneration leading to...
Autores principales: | Turner, Dennis A., Degan, Simone, Hoffmann, Ulrike, Galeffi, Francesca, Colton, Carol A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277667/ https://www.ncbi.nlm.nih.gov/pubmed/33656270 http://dx.doi.org/10.1002/alz.12289 |
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