IL-15 and PIM kinases direct the metabolic programming of intestinal intraepithelial lymphocytes

Intestinal intraepithelial lymphocytes (IEL) are an abundant population of tissue-resident T cells that protect and maintain the intestinal barrier. IEL respond to epithelial cell-derived IL-15, which is complexed to the IL-15 receptor α chain (IL-15/Rα). IL-15 is essential both for maintaining IEL...

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Detalles Bibliográficos
Autores principales: James, Olivia J., Vandereyken, Maud, Marchingo, Julia M., Singh, Francois, Bray, Susan E., Wilson, Jamie, Love, Andrew G., Swamy, Mahima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277781/
https://www.ncbi.nlm.nih.gov/pubmed/34257288
http://dx.doi.org/10.1038/s41467-021-24473-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277781/
https://www.ncbi.nlm.nih.gov/pubmed/34257288
http://dx.doi.org/10.1038/s41467-021-24473-2

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