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HLA-DR cancer cells expression correlates with T cell infiltration and is enriched in lung adenocarcinoma with indolent behavior

Lung adenocarcinoma (ADC) is a heterogeneous group of tumors associated with different survival rates, even when detected at an early stage. Here, we aim to investigate whether CyTOF identifies cellular and molecular predictors of tumor behavior. We developed and validated a CyTOF panel of 34 antibo...

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Detalles Bibliográficos
Autores principales: Senosain, Maria-Fernanda, Zou, Yong, Novitskaya, Tatiana, Vasiukov, Georgii, Balar, Aneri B., Rowe, Dianna J., Doxie, Deon B., Lehman, Jonathan M., Eisenberg, Rosana, Maldonado, Fabien, Zijlstra, Andries, Novitskiy, Sergey V., Irish, Jonathan M., Massion, Pierre P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277797/
https://www.ncbi.nlm.nih.gov/pubmed/34257356
http://dx.doi.org/10.1038/s41598-021-93807-3