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Finite element analysis predicts Ca(2+) microdomains within tubular-sarcoplasmic reticular junctions of amphibian skeletal muscle

A finite element analysis modelled diffusional generation of steady-state Ca(2+) microdomains within skeletal muscle transverse (T)-tubular-sarcoplasmic reticular (SR) junctions, sites of ryanodine receptor (RyR)-mediated SR Ca(2+) release. It used established quantifications of sarcomere and T-SR a...

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Detalles Bibliográficos
Autores principales: Bardsley, Oliver J., Matthews, Hugh R., Huang, Christopher L.-H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277803/
https://www.ncbi.nlm.nih.gov/pubmed/34257321
http://dx.doi.org/10.1038/s41598-021-93083-1