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miR-301a-3p induced by endoplasmic reticulum stress mediates the occurrence and transmission of trastuzumab resistance in HER2-positive gastric cancer

Trastuzumab resistance negatively influences the clinical efficacy of the therapy for human epidermal growth factor receptor 2 (HER2) positive gastric cancer (GC), and the underlying mechanisms remain elusive. Exploring the mechanisms and finding effective approaches to address trastuzumab resistanc...

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Detalles Bibliográficos
Autores principales: Guo, Jing, Zhong, Xuxian, Tan, Qinglin, Yang, Shengnan, Liao, Jiaqi, Zhuge, Jinke, Hong, Ziyang, Deng, Qiong, Zuo, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277821/
https://www.ncbi.nlm.nih.gov/pubmed/34257270
http://dx.doi.org/10.1038/s41419-021-03991-3