Endoplasmic reticulum phospholipid scramblase activity revealed after protein reconstitution into giant unilamellar vesicles containing a photostable lipid reporter

Transbilayer movement of phospholipids in biological membranes is mediated by a diverse set of lipid transporters. Among them are scramblases that facilitate a rapid bi-directional movement of lipids without metabolic energy input. Here, we established a new fluorescence microscopy-based assay for d...

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Detalles Bibliográficos
Autores principales: Mathiassen, Patricia P. M., Menon, Anant K., Pomorski, Thomas Günther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277826/
https://www.ncbi.nlm.nih.gov/pubmed/34257324
http://dx.doi.org/10.1038/s41598-021-93664-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277826/
https://www.ncbi.nlm.nih.gov/pubmed/34257324
http://dx.doi.org/10.1038/s41598-021-93664-0

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