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Endoplasmic reticulum phospholipid scramblase activity revealed after protein reconstitution into giant unilamellar vesicles containing a photostable lipid reporter
Transbilayer movement of phospholipids in biological membranes is mediated by a diverse set of lipid transporters. Among them are scramblases that facilitate a rapid bi-directional movement of lipids without metabolic energy input. Here, we established a new fluorescence microscopy-based assay for d...
Autores principales: | Mathiassen, Patricia P. M., Menon, Anant K., Pomorski, Thomas Günther |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277826/ https://www.ncbi.nlm.nih.gov/pubmed/34257324 http://dx.doi.org/10.1038/s41598-021-93664-0 |
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