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An in vitro investigation to understand the synergistic role of MMPs-1 and 9 on articular cartilage biomechanical properties

Matrix metalloproteinases (MMPs) play a crucial role in enzymatically digesting cartilage extracellular matrix (ECM) components, resulting in degraded cartilage with altered mechanical loading capacity. Overexpression of MMPs is often caused by trauma, physiologic conditions and by disease. To under...

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Detalles Bibliográficos
Autores principales: Mixon, Allison, Savage, Andrew, Bahar-Moni, Ahmed Suparno, Adouni, Malek, Faisal, Tanvir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277889/
https://www.ncbi.nlm.nih.gov/pubmed/34257325
http://dx.doi.org/10.1038/s41598-021-93744-1