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An in vitro investigation to understand the synergistic role of MMPs-1 and 9 on articular cartilage biomechanical properties
Matrix metalloproteinases (MMPs) play a crucial role in enzymatically digesting cartilage extracellular matrix (ECM) components, resulting in degraded cartilage with altered mechanical loading capacity. Overexpression of MMPs is often caused by trauma, physiologic conditions and by disease. To under...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277889/ https://www.ncbi.nlm.nih.gov/pubmed/34257325 http://dx.doi.org/10.1038/s41598-021-93744-1 |