Differential effects of SUMO1 and SUMO2 on circadian protein PER2 stability and function

Posttranslational modification (PTM) of core circadian clock proteins, including Period2 (PER2), is required for proper circadian regulation. PER2 function is regulated by casein kinase 1 (CK1)-mediated phosphorylation and ubiquitination but little is known about other PER2 PTMs or their interaction...

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Detalles Bibliográficos
Autores principales: Chen, Ling-Chih, Hsieh, Yung-Lin, Tan, Grace Y. T., Kuo, Tai-Yun, Chou, Yu-Chi, Hsu, Pang-Hung, Hwang-Verslues, Wendy W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277905/
https://www.ncbi.nlm.nih.gov/pubmed/34257372
http://dx.doi.org/10.1038/s41598-021-93933-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277905/
https://www.ncbi.nlm.nih.gov/pubmed/34257372
http://dx.doi.org/10.1038/s41598-021-93933-y

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