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Computational Drug Repurposing for Alzheimer’s Disease Using Risk Genes From GWAS and Single-Cell RNA Sequencing Studies

Background: Traditional therapeutics targeting Alzheimer’s disease (AD)-related subpathologies have so far proved ineffective. Drug repurposing, a more effective strategy that aims to find new indications for existing drugs against other diseases, offers benefits in AD drug development. In this stud...

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Detalles Bibliográficos
Autores principales: Xu, Yun, Kong, Jiming, Hu, Pingzhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277916/
https://www.ncbi.nlm.nih.gov/pubmed/34276354
http://dx.doi.org/10.3389/fphar.2021.617537