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Ocular benzalkonium chloride exposure: problems and solutions

Preservatives in multidose formulations of topical ophthalmic medications are crucial for maintaining sterility but can be toxic to the ocular surface. Benzalkonium chloride (BAK)—used in approximately 70% of ophthalmic formulations—is well known to cause cytotoxic damage to conjunctival and corneal...

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Detalles Bibliográficos
Autores principales: Goldstein, Michael H., Silva, Fabiana Q., Blender, Nysha, Tran, Trung, Vantipalli, Srilatha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277985/
https://www.ncbi.nlm.nih.gov/pubmed/34262161
http://dx.doi.org/10.1038/s41433-021-01668-x