Pseudolaric acid B ameliorates synovial inflammation and vessel formation by stabilizing PPARγ to inhibit NF‐κB signalling pathway

Synovial macrophage polarization and inflammation are essential for osteoarthritis (OA) development, yet the molecular mechanisms and regulation responsible for the pathogenesis are still poorly understood. Here, we report that pseudolaric acid B (PAB) attenuated articular cartilage degeneration and...

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Detalles Bibliográficos
Autores principales: Lu, Jiansen, Guan, Hong, Wu, Dan, Hu, Zhiqiang, Zhang, Hongbo, Jiang, Huaji, Yu, Jingyao, Zeng, Ke, Li, Hongyu, Zhang, Haiyan, Pan, Chenglong, Cai, Daozhang, Yu, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278075/
https://www.ncbi.nlm.nih.gov/pubmed/34117708
http://dx.doi.org/10.1111/jcmm.16670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278075/
https://www.ncbi.nlm.nih.gov/pubmed/34117708
http://dx.doi.org/10.1111/jcmm.16670

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