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Pseudolaric acid B ameliorates synovial inflammation and vessel formation by stabilizing PPARγ to inhibit NF‐κB signalling pathway
Synovial macrophage polarization and inflammation are essential for osteoarthritis (OA) development, yet the molecular mechanisms and regulation responsible for the pathogenesis are still poorly understood. Here, we report that pseudolaric acid B (PAB) attenuated articular cartilage degeneration and...
Autores principales: | Lu, Jiansen, Guan, Hong, Wu, Dan, Hu, Zhiqiang, Zhang, Hongbo, Jiang, Huaji, Yu, Jingyao, Zeng, Ke, Li, Hongyu, Zhang, Haiyan, Pan, Chenglong, Cai, Daozhang, Yu, Xiao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278075/ https://www.ncbi.nlm.nih.gov/pubmed/34117708 http://dx.doi.org/10.1111/jcmm.16670 |
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