The P300/XBP1s/Herpud1 axis promotes macrophage M2 polarization and the development of choroidal neovascularization

Neovascular age‐related macular degeneration (AMD), which is characterized by choroidal neovascularization (CNV), leads to vision loss. M2 macrophages produce vascular endothelial growth factor (VEGF), which aggravates CNV formation. The histone acetyltransferase p300 enhances the stability of splic...

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Detalles Bibliográficos
Autores principales: Li, Wendie, Wang, Ying, Zhu, Linling, Du, Shu, Mao, Jinghai, Wang, Yanyan, Wang, Sangsang, Bo, Qingyun, Tu, Yuanyuan, Yi, QuanYong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278076/
https://www.ncbi.nlm.nih.gov/pubmed/34057287
http://dx.doi.org/10.1111/jcmm.16673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278076/
https://www.ncbi.nlm.nih.gov/pubmed/34057287
http://dx.doi.org/10.1111/jcmm.16673

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