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The P300/XBP1s/Herpud1 axis promotes macrophage M2 polarization and the development of choroidal neovascularization
Neovascular age‐related macular degeneration (AMD), which is characterized by choroidal neovascularization (CNV), leads to vision loss. M2 macrophages produce vascular endothelial growth factor (VEGF), which aggravates CNV formation. The histone acetyltransferase p300 enhances the stability of splic...
Autores principales: | Li, Wendie, Wang, Ying, Zhu, Linling, Du, Shu, Mao, Jinghai, Wang, Yanyan, Wang, Sangsang, Bo, Qingyun, Tu, Yuanyuan, Yi, QuanYong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278076/ https://www.ncbi.nlm.nih.gov/pubmed/34057287 http://dx.doi.org/10.1111/jcmm.16673 |
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