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Mutation of the novel acetylation site at K414R of BECN1 is involved in adipocyte differentiation and lipolysis

BECN1, a protein essential for autophagy, is involved in adipocyte differentiation, lipolysis and insulin resistance. The discovery of new mechanisms for modifying BECN1 in adipocytes may provide novel therapeutic targets for obesity. This study aimed to investigate the impact of mutations at the ac...

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Detalles Bibliográficos
Autores principales: Li, Chengqian, Xu, Jun, Yu, Qing, Wang, Ping, Dong, Bingzi, Shen, Liyan, Wang, Qing, Li, Shufa, Yang, Ying, Deng, Yujie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278081/
https://www.ncbi.nlm.nih.gov/pubmed/34085745
http://dx.doi.org/10.1111/jcmm.16692