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Mutation of the novel acetylation site at K414R of BECN1 is involved in adipocyte differentiation and lipolysis
BECN1, a protein essential for autophagy, is involved in adipocyte differentiation, lipolysis and insulin resistance. The discovery of new mechanisms for modifying BECN1 in adipocytes may provide novel therapeutic targets for obesity. This study aimed to investigate the impact of mutations at the ac...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278081/ https://www.ncbi.nlm.nih.gov/pubmed/34085745 http://dx.doi.org/10.1111/jcmm.16692 |