Pro‐inflammatory signals induce 20α‐HSD expression in myometrial cells: A key mechanism for local progesterone withdrawal

Metabolism of progesterone (P4) by the enzyme 20α hydroxysteroid dehydrogenase (20α‐HSD) in myometrial cells is postulated to be a mechanism for P4 withdrawal, which occurs concomitant to uterine inflammation (physiologic or infection‐induced) and associated activation of transcription factors: NF‐к...

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Detalles Bibliográficos
Autores principales: Nadeem, Lubna, Balendran, Rathesh, Dorogin, Anna, Mesiano, Sam, Shynlova, Oksana, Lye, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278114/
https://www.ncbi.nlm.nih.gov/pubmed/34114342
http://dx.doi.org/10.1111/jcmm.16681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278114/
https://www.ncbi.nlm.nih.gov/pubmed/34114342
http://dx.doi.org/10.1111/jcmm.16681

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