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The increased expression and aberrant methylation of SHC1 in non–small cell lung cancer: Integrative analysis of clinical and bioinformatics databases

Despite the previous evidence showing that SHC adaptor protein 1 (SHC1) could encode three distinct isoforms (p46SHC, p52SHC and p66SHC) that function in different activities such as regulating life span and Ras activation, the precise underlying role of SHC1 in lung cancer also remains obscure. In...

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Detalles Bibliográficos
Autores principales: Liang, Yicheng, Lei, Yangyang, Du, Minjun, Liang, Mei, Liu, Zixu, Li, Xingkai, Gao, Yushun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278126/
https://www.ncbi.nlm.nih.gov/pubmed/34117717
http://dx.doi.org/10.1111/jcmm.16717