Synthesis of New 1H-1,2,3-Triazole Analogs in Aqueous Medium via “Click” Chemistry: A Novel Class of Potential Carbonic Anhydrase-II Inhibitors

A series of novel 1H-1,2,3-triazole analogs (9a–j) were synthesized via “Click” chemistry and Suzuki–Miyaura cross-coupling reaction in aqueous medium. The compounds were evaluated for their carbonic anhydrase-II enzyme inhibitory activity in vitro. The synthesis of triazole 7a was accomplished usin...

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Detalles Bibliográficos
Autores principales: Avula, Satya Kumar, Khan, Majid, Halim, Sobia Ahsan, Khan, Ajmal, Al-Riyami, Samia Ahmed, Csuk, Rene, Das, Biswanath, Al-Harrasi, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278147/
https://www.ncbi.nlm.nih.gov/pubmed/34277561
http://dx.doi.org/10.3389/fchem.2021.642614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278147/
https://www.ncbi.nlm.nih.gov/pubmed/34277561
http://dx.doi.org/10.3389/fchem.2021.642614

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