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Finding the Ion in the RNA-Stack: Can Computational Models Accurately Predict Key Functional Elements in Large Macromolecular Complexes?

[Image: see text] This viewpoint discusses the predictive power and impact of computational analyses and simulations to gain prospective, experimentally supported mechanistic insights into complex biological systems. Remarkably, two newly resolved cryoEM structures have confirmed the previous, and i...

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Detalles Bibliográficos
Autores principales: Marcia, Marco, Manigrasso, Jacopo, De Vivo, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278382/
https://www.ncbi.nlm.nih.gov/pubmed/34133879
http://dx.doi.org/10.1021/acs.jcim.1c00572