Amplification of mutant KRAS(G12D) in a patient with advanced metastatic pancreatic adenocarcinoma detected by liquid biopsy: A case report

Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest cancer types. Activating oncogenic KRAS mutations are commonly observed in PDAC; however, oncogenic KRAS amplification is rarely observed, and its significance in prognosis and resistance to therapy remains poorly characterized. Th...

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Detalles Bibliográficos
Autores principales: Pittella-Silva, Fabio, Kimura, Yasutoshi, Low, Siew-Kee, Nakamura, Yusuke, Motoya, Masayo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278405/
https://www.ncbi.nlm.nih.gov/pubmed/34276991
http://dx.doi.org/10.3892/mco.2021.2334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278405/
https://www.ncbi.nlm.nih.gov/pubmed/34276991
http://dx.doi.org/10.3892/mco.2021.2334

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