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Apoptotic inducement of neuronal cells by codeine: possible role of disrupted redox state and caspase 3 signaling

BACKGROUND: Codeine, a common drug of abuse, has been reported to induce organ damage; however, there are scanty available data on the effects of codeine on the brain. OBJECTIVE: Thus, we tested the hypothesis that redox dysregulation and inflammation of the brain induced by codeine exposure is 8-OH...

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Detalles Bibliográficos
Autores principales: Ajayi, A.F., Akhigbe, R.E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278432/
https://www.ncbi.nlm.nih.gov/pubmed/34286140
http://dx.doi.org/10.1016/j.heliyon.2021.e07481