HDAC4 Knockdown Alleviates Denervation-Induced Muscle Atrophy by Inhibiting Myogenin-Dependent Atrogene Activation

Denervation can activate the catabolic pathway in skeletal muscle and lead to progressive skeletal muscle atrophy. At present, there is no effective treatment for muscle atrophy. Histone deacetylase 4 (HDAC4) has recently been found to be closely related to muscle atrophy, but the underlying mechani...

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Detalles Bibliográficos
Autores principales: Ma, Wenjing, Cai, Yong, Shen, Yuntian, Chen, Xin, Zhang, Lilei, Ji, Yanan, Chen, Zehao, Zhu, Jianwei, Yang, Xiaoming, Sun, Hualin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278478/
https://www.ncbi.nlm.nih.gov/pubmed/34276308
http://dx.doi.org/10.3389/fncel.2021.663384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278478/
https://www.ncbi.nlm.nih.gov/pubmed/34276308
http://dx.doi.org/10.3389/fncel.2021.663384

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