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Insights into the molecular basis of the palmitoylation and depalmitoylation of NCX1

Catalyzed by zDHHC-PAT enzymes and reversed by thioesterases, protein palmitoylation is the only post-translational modification recognized to regulate the sodium/calcium exchanger NCX1. NCX1 palmitoylation occurs at a single site at position 739 in its large regulatory intracellular loop. An amphip...

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Detalles Bibliográficos
Autores principales: Gök, Caglar, Main, Alice, Gao, Xing, Kerekes, Zsombor, Plain, Fiona, Kuo, Chien-Wen, Robertson, Alan D., Fraser, Niall J., Fuller, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278489/
https://www.ncbi.nlm.nih.gov/pubmed/33873072
http://dx.doi.org/10.1016/j.ceca.2021.102408