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Structure of the TELO2-TTI1-TTI2 complex and its function in TOR recruitment to the R2TP chaperone

The R2TP (RUVBL1-RUVBL2-RPAP3-PIH1D1) complex, in collaboration with heat shock protein 90 (HSP90), functions as a chaperone for the assembly and stability of protein complexes, including RNA polymerases, small nuclear ribonucleoprotein particles (snRNPs), and phosphatidylinositol 3-kinase (PI3K)-li...

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Detalles Bibliográficos
Autores principales: Pal, Mohinder, Muñoz-Hernandez, Hugo, Bjorklund, Dennis, Zhou, Lihong, Degliesposti, Gianluca, Skehel, J. Mark, Hesketh, Emma L., Thompson, Rebecca F., Pearl, Laurence H., Llorca, Oscar, Prodromou, Chrisostomos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278493/
https://www.ncbi.nlm.nih.gov/pubmed/34233195
http://dx.doi.org/10.1016/j.celrep.2021.109317