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Structure of the TELO2-TTI1-TTI2 complex and its function in TOR recruitment to the R2TP chaperone
The R2TP (RUVBL1-RUVBL2-RPAP3-PIH1D1) complex, in collaboration with heat shock protein 90 (HSP90), functions as a chaperone for the assembly and stability of protein complexes, including RNA polymerases, small nuclear ribonucleoprotein particles (snRNPs), and phosphatidylinositol 3-kinase (PI3K)-li...
Autores principales: | Pal, Mohinder, Muñoz-Hernandez, Hugo, Bjorklund, Dennis, Zhou, Lihong, Degliesposti, Gianluca, Skehel, J. Mark, Hesketh, Emma L., Thompson, Rebecca F., Pearl, Laurence H., Llorca, Oscar, Prodromou, Chrisostomos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278493/ https://www.ncbi.nlm.nih.gov/pubmed/34233195 http://dx.doi.org/10.1016/j.celrep.2021.109317 |
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