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Efficiency and Toxicity of Ruxolitinib as a Salvage Treatment for Steroid-Refractory Chronic Graft-Versus-Host Disease

Graft-versus-host disease (GVHD), especially steroid-refractory GVHD, remains a life-threatening complication after hematopoietic stem cell transplantation (HSCT). The effect of the JAK1/2 kinase inhibitor ruxolitinib on treating steroid-refractory acute GVHD has been verified by the REACH1/2 study;...

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Detalles Bibliográficos
Autores principales: Wang, Dong, Liu, Yin, Lai, Xiaoxuan, Chen, Jia, Cheng, Qiao, Ma, Xiao, Lin, Zhihong, Wu, Depei, Xu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278571/
https://www.ncbi.nlm.nih.gov/pubmed/34276662
http://dx.doi.org/10.3389/fimmu.2021.673636