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Exosome-transported circRNA_0001236 enhances chondrogenesis and suppress cartilage degradation via the miR-3677-3p/Sox9 axis

OBJECTIVES: Aberrations in exosomal circular RNA (circRNA) expression have been identified in various human diseases. In this study, we investigated whether exosomal circRNAs could act as competing endogenous RNAs (ceRNAs) to regulate the pathological process of osteoarthritis (OA). This study aimed...

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Detalles Bibliográficos
Autores principales: Mao, Guping, Xu, Yiyang, Long, Dianbo, Sun, Hong, Li, Hongyi, Xin, Ruobin, Zhang, Ziji, Li, Zhiwen, Yang, Zhi, Kang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278601/
https://www.ncbi.nlm.nih.gov/pubmed/34256841
http://dx.doi.org/10.1186/s13287-021-02431-5