Downregulation of tumor‐derived exosomal miR-34c induces cancer‐associated fibroblast activation to promote cholangiocarcinoma progress

BACKGROUND: This study aimed to investigate the exact regulatory mechanisms of exosomal miR-34c in mediating communication between cholangiocarcinoma cells and fibroblasts. METHODS: Exosomes were isolated from HuCCT-1 and HIBEC cells using differential ultracentrifugation and identified by transmiss...

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Detalles Bibliográficos
Autores principales: Qin, Xinglei, Lu, Min, Li, Gang, Zhou, Yajun, Liu, Zhaoyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278610/
https://www.ncbi.nlm.nih.gov/pubmed/34261453
http://dx.doi.org/10.1186/s12935-020-01726-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278610/
https://www.ncbi.nlm.nih.gov/pubmed/34261453
http://dx.doi.org/10.1186/s12935-020-01726-6

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