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tRNA derived fragment (tRF)-3009 participates in modulation of IFN-α-induced CD4(+) T cell oxidative phosphorylation in lupus patients

BACKGROUND: Accumulating evidence suggests tRNA-derived fragments (tRFs) play important roles in cellular homeostasis. Here we aimed to explore aberrant expression of tRFs in CD4(+) T cells from patients with systemic lupus erythematosus (SLE) and their potential function in the SLE pathogenesis. ME...

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Detalles Bibliográficos
Autores principales: Geng, Guannan, Wang, Huijing, Xin, Weiwei, Liu, Zhe, Chen, Jie, Danting, Zhang, Han, Fei, Ye, Shuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278670/
https://www.ncbi.nlm.nih.gov/pubmed/34256772
http://dx.doi.org/10.1186/s12967-021-02967-3