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Plasma interferon-alpha is associated with double-positivity for autoantibodies but is not a predictor of remission in early rheumatoid arthritis—a spin-off study of the NORD-STAR randomized clinical trial

BACKGROUND: The type I interferon (IFN) gene signature is present in a subgroup of patients with early rheumatoid arthritis (RA). Protein levels of IFNα have not been measured in RA and it is unknown whether they associate with clinical characteristics or treatment effect. METHODS: Patients with ear...

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Detalles Bibliográficos
Autores principales: Stockfelt, Marit, Lundell, Anna-Carin, Hetland, Merete Lund, Østergaard, Mikkel, Uhlig, Till, Heiberg, Marte Schrumpf, Haavardsholm, Espen A., Nurmohamed, Michael T., Lampa, Jon, Nordström, Dan, Petersen, Kim Hørslev, Gudbjornsson, Bjorn, Gröndal, Gerdur, Aldridge, Jonathan, Andersson, Kerstin, Blennow, Kaj, Zetterberg, Henrik, van Vollenhoven, Ronald, Rudin, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278690/
https://www.ncbi.nlm.nih.gov/pubmed/34256800
http://dx.doi.org/10.1186/s13075-021-02556-1