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Novel Mixed NOP/Opioid Receptor Peptide Agonists

[Image: see text] The nociceptin/orphanin FQ (N/OFQ)/N/OFQ receptor (NOP) system controls different biological functions including pain and cough reflex. Mixed NOP/opioid receptor agonists elicit similar effects to strong opioids but with reduced side effects. In this work, 31 peptides with the gene...

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Detalles Bibliográficos
Autores principales: Pacifico, Salvatore, Albanese, Valentina, Illuminati, Davide, Marzola, Erika, Fabbri, Martina, Ferrari, Federica, Holanda, Victor A.D., Sturaro, Chiara, Malfacini, Davide, Ruzza, Chiara, Trapella, Claudio, Preti, Delia, Lo Cascio, Ettore, Arcovito, Alessandro, Della Longa, Stefano, Marangoni, Martina, Fattori, Davide, Nassini, Romina, Calò, Girolamo, Guerrini, Remo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279409/
https://www.ncbi.nlm.nih.gov/pubmed/33998786
http://dx.doi.org/10.1021/acs.jmedchem.0c02062